VenaFlux Platforms

Automated microfluidic platform capable of executing cell rolling, binding/adhesion and migration studies under shear flow mimicking in vivo flow rates.

The VenaFluxTM Platform is the first semi-automated microfluidic platform capable of executing cell rolling, binding/adhesion and migration studies under shear flow mimicking in vivo flow rates.  

Features:

  • Robust and easy to use
  • Ideal for use with whole blood for platelet adhesion, aggregation and thrombi formation (thrombosis); biofilm culture ove extended periods of time.
  • Easy to study cell adhesion, migration and transmigration - more physiologically relevant than static assays.
  • Excellent platform for in vitro studies and running experiments in parallel with animal models.

Applications:  

  • Functional cell-ligand and cell-cell interaction studies.
  • Morphology analysis of cell adhesion and migration.
  • Tracking of flowing, rolling and migrating cells.
  • IC50 curves easily produced.
  • Preclinical drug development and lead optimization.